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Закон о рациональном природопользовании (Environmental Management Act itisasecret) EMA сокр. : английский тезаурус воен. electromagnetic analysis; emergency assistance; emergency movements, atomic; engine maintenance area; equipment maintenance agreement комп. electromagnetic actuator сокр. eMarketing Association; Emergency Management Agency; Ethnic Minority Achievement; European Manipuri Association; Extended Maintenance Agreement; East Midlands Airport ( gconnell); Electronics Manufacturers Association; Electronics Material Agency; Electronics Materiel Agency; Emergency Minerals Administration (US); Europe, Middle East and Africa ( Метран); European Marketing Association; European Monetary Agreement; Extended Mercury Autocode; End of Module Assessment ( Johnny Bravo) сокр., ав. East Midlands, England, UK; electromagnetic analyzer; in the event of a missed approach сокр., бирж. Exponential Moving Average сокр., воен., ав. electromechanical actuation сокр., вчт. Electronic Management Automation; Encina Monitor Administration; Enterprise Management Architecture сокр., геод. Elevation Mask Angle (GPS Yuri Ginsburg) сокр., гироск. electromagnetic accelerometer сокр., джейн. Electromagnetic Armour; Electronic Missile Acquisition; External Mounting Assembly сокр., иммун. epithelial membrane antigen сокр., комп. Electronic Mail/Messaging Association ( Vosoni) сокр., Макаров. the effective mass approximation сокр., маркет. Executive Marketing Assistant ( Sloneno4eg) сокр., мед. Emergency Medical Assistant; Emergency Medical Attendant; EMEA ( MichaelBurov); European Medicines Agency ( MichaelBurov); Emergent Medical Associates сокр., муз. European Music Awards сокр., нефт. equivalent methane in air сокр., нефтегаз. Engine Manufacturers Association сокр., образ. End-of-Module Assessment ( Johnny Bravo) сокр., образ., научн. Educational Maintenance Allowance сокр., опт. extramural absorption сокр., почт. Emergency Management Activity; Envelope Manufacturers Association (industry trade association); Equipment Maintenance Allowance (i. e. mileage for private car) сокр., радио., научн. E Mail Address сокр., с. х. Environmental Management For Agriculture сокр., сеть. Electronic Mail Association; Electronic Manufacturers Association; Electronic Messaging Association сокр., сеть., вчт. External Model Access сокр., т. м. Educational Media Association сокр., тех. Copolymer From Ethylene and Methacrylic Acid ( Vosoni) сокр., ф. расш. Enterprise Management/Memory Architecture сокр., физиол., мед. Extra Muscular Action сокр., хим., научн. Ethylene Methacrylic Acid сокр., эл., научн. Easy Magnetization Axis сокр., юр. Education Maintenance Allowance; Emotionally Motivated Agent тех. electronic maintenance assembly; electronic measuring apparatus; extended memory area PEMA сокр. procurement of equipment and missiles, Army Ema сокр. рел. Small wooden tablets, usually five-sided and about the size of a hand, distributed at Shinto shrines and Buddhist temples all over Japan. Ema means 'horse-picture' and was perhaps in origin (the earliest known ema date from the eighth century) a substitute for a horse offered to the shrine as a messenger or servant of the kami. In the Muromachi and Tokugawa periods o-ema (large sized ema) developed as a professional art form, and were offered to temple-shrines and exhibited in emado (ema-halls) as thanks for some benefit received or for their artistic merit, a custom which continues. Pictorial conventions developed among professional manufacturers of small ema, so that a dog depicted easy birth (as in the hara-obi), a phallus represented fertility, a padlock over the character kokoro (heart) indicated a vow of abstinence and so forth. Ema today frequently carry on one side a picture of the current year-animal (see Juni-shi) such as a dragon, snake or monkey and a pattern or image related to the shrine from which they are obtained, including in some cases the riyaku for which the shrine is known. On the other side shrine visitors inscribe their name, address and personal o-negai (prayerful request) either for a specific problem to be resolved or more generally for benefits such as good health or success in examinations ( gokaku), work or marriage. Ema may also embody a vow, a message to a spirit, an ancestor or dead relative including an aborted baby (mizuko), thanks or appreciation for a successful recovery or a statement of resolve. Unlike talismans and amulets (o-fuda, o-mamori) which embody the spirit of the kami and are taken away, ema are messages to the kami or bostatsu which are posted at the shrine, but along with o-fuda and o-mamori the old year's ema are normally burnt at New Year A Popular Dictionary of Shinto (Brian Bocking) EPMA сокр. electron probe microanalyser.
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Emma's blog. Emma chamberlain coffee. Emma trailer 2020. Emma drobná words. Emma king. Je to dojemné a každý komu umřel děda si na něj vzpomene,kdo dal dislike toho absolutně nechápu. Emma drobna. Emma chamberlain tiktok. Suomalaiset valtaa taas kommentit🇫🇮. Emma walton hamilton. Emma pretend play youtube. Go girl, go. Much love from France <3 <3 <3. Emma mackey margot robbie. Emma samms. Emma frost. Emma topp. Emma hill. Emma bloomberg. Emma and wendy. European Medicines Agency Agency overview Formed 1 January 1995; 25 years ago Jurisdiction European Union Headquarters Amsterdam, Netherlands  Motto Science. Medicines. Health. Agency executives Guido Rasi, Executive Director Christa Wirthumer-Hoche, Chairperson Key document Regulation (EC) No. 726/2004 Website ema Map Amsterdam European Medicines Agency (European Union) European Union This article is part of a series on the politics and government of the European Union Member States (27) Austria Belgium Bulgaria Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Ireland Italy Latvia Lithuania Luxembourg Malta Netherlands Poland Portugal Romania Slovakia Slovenia Spain Sweden Presidency of the Council of the EU Croatia (January - June 2020) Candidate countries Albania Bosnia and Herzegovina Montenegro North Macedonia Serbia Turkey Special member state territories EU 3 Withdrawal from the European Union The Treaties Treaty of Paris (1951) Treaty of Rome (1957) Euratom Treaty (1957) Merger Treaty (1965) Single European Act (1986) Maastricht Treaty (1992) Amsterdam Treaty (1997) Treaty of Nice (2001) Treaty of Lisbon (2007) Article 7 Article 50 Opt-outs Treaties of Accession 1972, 1979, 1985, 1994, 2003, 2005, 2011 Other Treaties Schengen Agreement (1985) EEA Agreement (1992) Brexit Withdrawal Agreement (2018) Abandoned treaties and agreements European Constitution (2004) UK renegotiation of EU membership (2015-16) Executive European Council President: Michel (ALDE) Parties List of meetings European Commission Von der Leyen Commission President: Von der Leyen (EPP) Vice Presidents College of Commissioners Civil Service Secretary-General: Juhansone Legislature Legislative procedure Council of the EU ( Presidency) Configurations General Foreign Economic Eurogroup Justice and Home Voting Secretariat Secretary-General: Uwe Corsepius Directorates-general COREPER European Parliament ( Members) President: Sassoli (S&D) Largest groups EPP ( Manfred Weber) S&D ( Iratxe García) Member of the European Parliament 9th session (2019–24) Bureau Quaestor Conference National parliaments Judiciary Court of Justice of the EU Court of Justice Members Rulings General Court Euro Eurozone Members Austria Belgium Cyprus Estonia Finland France Germany Greece Ireland Italy Latvia Lithuania Luxembourg Malta Netherlands Portugal Slovakia Slovenia Spain President Mário Centeno European Central Bank President Draghi ESCB EMU Schengen Area Participating Schengen Area States Czech Republic Denmark Hungary Iceland (non-EU state) Liechtenstein (non-EU state) Norway (non-EU state) Poland Sweden Switzerland (non-EU state) Prüm Convention Schengen Information System Visa Information System Visa policy of the Schengen Area European Economic Area EEA Members Bulgaria Romania United Kingdom (non-EU state) Gibraltar EEA Joint Committee EEA National Identity cards Microstates and the European Union Court of Auditors Budget OLAF Other Bodies European Atomic Energy Community Agencies Investment Bank CoR EESC Ombudsman Former European Bodies European Communities (1958-1993) European Coal and Steel Community European Economic Community Law Acquis Primacy Subsidiarity Regulation Directive Decision Fundamental Rights Policies and Issues Customs Union Free Trade Agreements European Single Market Area of FS&J Policies Agricultural Energy Fisheries Regional Citizenship Passports of the European Union Identity Pro-Europeanism Euroscepticism Integration Supranationalism Federalism United States of Europe Enhanced co-op Elections 1979, 1984, 1989, 1994 1999, 2004, 2009, 2014 2019 (last election) Political parties Constituencies Referendums Other Other currencies in use Bulgarian lev Croatian kuna Czech koruna Danish krone Hungarian forint Polish złoty Romanian leu Swedish krona ERM II Enlargement of the Eurozone Bulgaria and the euro Croatia and the euro Czech Republic and the euro Denmark and the euro Hungary and the euro Poland and the euro Sweden and the euro Romania and the euro Non-Schengen Area States Croatia Common Travel Area ( Ireland) Multi-speed Europe Foreign Relations High Representative Josep Borrell Foreign relations of EU Member States Ext. Action Service Foreign Policy Defence Policy European Union Association Agreement Norway–European Union relations Switzerland–European Union relations United Kingdom–European Union relations United States-European Union relations European Union and the United Nations G7 G20 European Union portal Other countries Atlas v t e The European Medicines Agency ( EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of medicinal products. Prior to 2004, it was known as the European Agency for the Evaluation of Medicinal Products or European Medicines Evaluation Agency ( EMEA).   The EMA was set up in 1995, with funding from the European Union and the pharmaceutical industry, as well as indirect subsidy from member states, its stated intention to harmonise (but not replace) the work of existing national medicine regulatory bodies. The hope was that this plan would not only reduce the €350 million annual cost drug companies incurred by having to win separate approvals from each member state but also that it would eliminate the protectionist tendencies of sovereign states unwilling to approve new drugs that might compete with those already produced by domestic drug companies. The EU is currently the source of about one-third of the new drugs brought onto the world market each year. [ not verified in body] The EMA was founded after more than seven years of negotiations among EU governments and replaced the Committee for Proprietary Medicinal Products and the Committee for Veterinary Medicinal Products, though both of these were reborn as the core scientific advisory committees. The agency was located in London prior to the United Kingdom's vote for withdrawal from the European Union, relocating to Amsterdam in March 2019.   Operations [ edit] The EMA operates as a decentralised scientific agency (as opposed to a regulatory authority) of the European Union and its main responsibility is the protection and promotion of public and animal health, through the evaluation and supervision of medicines for human and veterinary use. More specifically, it coordinates the evaluation and monitoring of centrally authorised products and national referrals, develops technical guidance and provides scientific advice to sponsors. Its scope of operations is medicinal products for human and veterinary use including biologics and advanced therapies, and herbal medicinal products. The agency is composed of the Secretariat (ca. 600 staff), a management board, seven scientific committees (human, veterinary and herbal medicinal products, orphan drugs, paediatrics, advanced therapies and pharmacovigilance risk assessment) and a number of scientific working parties. The Secretariat is organised into five units: Directorate, Human Medicines Development and Evaluation, Patient Health Protection, Veterinary Medicines and Product Data Management, Information and Communications Technology and Administration. The Management Board provides administrative oversight to the Agency: including approval of budgets and plans, and selection of Executive Director. The Board includes one representative of each of the 28 Member States, two representatives of the European Commission, two representatives of the European Parliament, two representatives of patients' organisations, one representative of doctors' organisations and one representative of veterinarians' organisations. The Agency decentralises its scientific assessment of medicines by working through a network of about 4500 experts throughout the EU. The EMA draws on resources of over 40 National Competent Authorities (NCAs) of EU Member states. [ edit] The centralised procedure allows companies to submit a single application to the agency to obtain from the European Commission a centralised (or 'Community') marketing authorisation (MA) valid in all EU and European Economic Area (EEA)- European Free Trade Association (EFTA) states ( Iceland, Liechtenstein and Norway). The centralised procedure is compulsory for all medicines derived from biotechnology and other high-tech processes, as well as for human medicines for the treatment of HIV/AIDS, cancer, diabetes, neurodegenerative diseases, auto-immune and other immune dysfunctions, and viral diseases, and for veterinary medicines for use for growth or yield enhancers. The centralised procedure is also open to products that bring a significant therapeutic, scientific or technical innovation, or is in any other respect in the interest of patient or animal health. As a result, the majority of genuinely novel medicines are authorised through the EMA. For products eligible for or requiring centralised approval, a company submits an application for a marketing authorisation to the EMA. [ citation needed] Committees [ edit] Committee for Medicinal Products for Human Use [ edit] A single evaluation is carried out through the Committee for Medicinal Products for Human Use (CHMP). If the Committee concludes that the quality, safety and efficacy of the medicinal product is sufficiently proven, it adopts a positive opinion. This is sent to the European Commission to be transformed into a marketing authorisation valid for the whole of the EU. A special type of approval is the paediatric-use marketing authorisation (PUMA), which can be granted for medical products intended exclusively for paediatric use.  The CHMP is obliged by the regulation to reach decisions within 210 days, though the clock is stopped if it is necessary to ask the applicant for clarification or further supporting data. [ citation needed] Committee for Medicinal Products for Veterinary Use [ edit] The Committee for Medicinal Products for Veterinary Use (CVMP) operates in analogy to the CHMP as described above. [ citation needed] Committee on Orphan Medicinal Products [ edit] The Committee on Orphan Medicinal Products (COMP) administers the granting of orphan drug status since 2000. Companies intending to develop medicinal products for the diagnosis, prevention or treatment of life-threatening or very serious conditions that affect not more than five in 10, 000 persons in the European Union can apply for 'orphan medicinal product designation'. The COMP evaluates the application and makes a recommendation for the designation which is then granted by the European Commission. [ citation needed] Committee on Herbal Medicinal Products [ edit] The Committee on Herbal Medicinal Products (HMPC) assists the harmonisation of procedures and provisions concerning herbal medicinal products laid down in EU Member States, and further integrating herbal medicinal products in the European regulatory framework since 2004. Paediatric Committee [ edit] The Paediatric Committee (PDCO) deals with the implementation of the paediatric legislation in Europe Regulation(EC) No 1901/2006 since 2007. Under this legislation, all applications for marketing authorisation of new medicinal products, or variations to existing authorisations, have to either include data from paediatric studies previously agreed with the PDCO, or obtain a PDCO waiver or a deferral of these studies. Committee for Advanced Therapies [ edit] The Committee for Advanced Therapies (CAT) was established in accordance with Regulation (EC) No 1394/2007 on advanced-therapy medicinal products (ATMPs) such as gene therapy, somatic cell therapy and tissue engineered products. It assesses the quality, safety and efficacy of ATMPs, and follows scientific developments in the field.  Pharmacovigilance Risk Assessment Committee [ edit] A seventh committee, the Pharmacovigilance Risk Assessment Committee (PRAC) has come into function in 2012 with the implementation of the new EU pharmacovigilance legislation (Directive 2010/84/EU).  Other activities [ edit] The Agency carries out a number of activities, including: Pharmacovigilance: The Agency constantly monitors the safety of medicines through a pharmacovigilance network and EudraVigilance, so that it can take appropriate actions if adverse drug reaction reports suggest that the benefit-risk balance of a medicine has changed since it was authorised. Referrals: The Agency coordinates arbitration procedures relating to medicinal products that are approved or under consideration by Member States in non-centralized authorisation procedures. Scientific Advice: Companies wishing to receive scientific advice from the CHMP or CVMP on the appropriate tests and studies to carry out in the development of a medicinal products can request it prior to or during the development program. Telematics projects: The Agency is responsible for implementing a central set of pan-European systems and databases such as EudraVigilance, EudraCT and EudraPharm. Relocation [ edit] Following the 2016 decision of the United Kingdom to leave the European Union (" Brexit "), the EMA chose to search for another base of operations. According to EU Law the European Commission had to decide on the fate of the EMA's location. The EU ministers met to vote on their preferred successor.  The EU's Health Commissioner Vytenis Andriukaitis said that the preferred choice would be a location where an "easy set up and guarantee of smooth operations" would be available. Member states who had expressed their bid for the new EMA location were Austria,  Belgium, Bulgaria,  Croatia,  Cyprus,  Czech Republic,  Denmark,  Finland,  France,  Germany,  Greece,  Hungary,  Ireland,  Italy,  Malta,  the Netherlands,  Poland,  Portugal,  Romania,   Slovakia,  Slovenia,  Spain,  and Sweden.    It had also been speculated that the Strasbourg -based seat for the European Parliament could be moved to Brussels, in exchange for the city to host the EMA.  Others speculated on the merits of Amsterdam, well before the final decision was made.   The decision on the relocation was made on 20 November 2017, during the EU General Affairs Council meeting,  after three voting rounds and finally drawing of lots. After the first round of voting, Milan (25 votes), Amsterdam (20 votes) and Copenhagen (20 votes) were the only contenders left.  After the second voting round, two cities were left: Milan (twelve votes) and Amsterdam (nine votes). These two cities tied in the subsequent vote (thirteen votes each), after which a drawing of lots identified Amsterdam as the host city of EMA. It is unclear what future arrangements the United Kingdom proposes to make for its own medicinal evaluation after leaving the EU. Paul Workman, the president of the London-based Institute of Cancer Research, has suggested that pharmaceutical companies would naturally seek regulatory approval for new drugs in the biggest markets first, leaving the UK facing delays in approval if they set up independent arrangements.  Criticism of the EMA process [ edit] The review process of the European Medicines Agency regarding medical issues has been criticized for its lack of transparency and issues of conflict of interest.  In a rebuttal of an EMS review that included her work, Louise Brinth, a Danish physician, noted that "experts" reviewing data remain unnamed and seem to be bound to secrecy. Minutes are not released and diverging opinions are not reported suggesting that all the "experts" are of the same opinion. In her view the process is unscientific and undemocratic.  Comparison with other regulatory agencies [ edit] The EMA is roughly parallel to the drug part of the U. S. Food and Drug Administration (FDA),  but without centralisation.  The timetable for product approval via the EMA's centralised procedure of 210 days compares well with the average of 500 days taken by the FDA to evaluate a product.  See also [ edit] References [ edit] ^ "Relocation to Amsterdam". European Medicines Agency. 17 September 2018. Retrieved 16 September 2019. ^ Set up by EC Regulation No. 2309/93 as the European Agency for the Evaluation of Medicinal Products, and renamed by EC Regulation No. 726/2004 to the European Medicines Agency, it had the acronym EMEA until December 2009. The European Medicines Agency does not call itself EMA either – it has no official acronym but may reconsider if EMA becomes commonly accepted (see communication on new visual identity Archived 1 June 2010 at the Wayback Machine and logo Archived 25 December 2009 at the Wayback Machine). ^ "EMEA becomes EMA". PMLive. 14 December 2009. ^ Hrabovszki, Georgina (11 March 2019). "EMA now operating from Amsterdam". Retrieved 12 March 2019. ^ "United Kingdom's withdrawal from the European Union ('Brexit')". Retrieved 16 September 2019. ^ "Questions and answers on the paediatric use marketing authorisation (PUMA)" (PDF). 13 September 2011. Archived from the original (PDF) on 15 April 2016. ^ European Medicines Agency (3 December 2019). "Committee for Advanced Therapies (CAT)". Retrieved 3 December 2019. ^ European Medicines Agency (3 December 2019). "Pharmacovigilance Risk Assessment Committee (PRAC)". Retrieved 3 December 2019. ^ "European Council - Offers to host the European Medicines Agency (EMA)". Retrieved 14 September 2017. ^ a b c d e f g h i j k l m n o "Reuters - Twenty-one countries vie to host EU drug agency after Brexit". Retrieved 10 August 2017. ^ a b "European Council - Offers to host the European Medicines Agency (EMA)". Retrieved 10 August 2017. ^ "Finland is an excellent place for European Medicines Agency". Sosiaali- ja terveysministeriö. Retrieved 18 April 2017. ^ "Homepage - The Dutch Bid for EMA". The Dutch Bid for EMA. Archived from the original on 14 July 2017. Retrieved 13 July 2017. ^ "Countries line up to host European Medicines Agency after it leaves UK". 15 February 2017. Retrieved 8 May 2017. ^ "Romania looks to poach EU medicines agency from UK". 23 March 2017. Retrieved 8 May 2017. ^ "A Brexit pill for Romania". 13 April 2017. Retrieved 8 May 2017. ^ Patrick Wintour. "Countries line up to host European Medicines Agency after it leaves UK | World news". The Guardian. Retrieved 1 April 2017. ^ Julia Bradshaw (8 December 2016). "Sweden launches campaign to host EU drugs agency instead of UK after Brexit".. Retrieved 1 April 2017. ^ Andreja Zapcic (29 March 2017). "Kujundžić: Hrvatska je spremna preuzeti Europsku agenciju za lijekove" (in Croatian).. Retrieved 1 April 2017. ^ "Strasbourg could trade Parliament seat for medicines agency". 10 May 2017. ^ "PharmaTimes, 27th September 2017. EMA staff favour move to Amsterdam". Retrieved 19 October 2017. ^ a b "Nature News, October 2017. European drug regulation at risk of stalling as agency prepares to leave London". Retrieved 13 October 2017. ^ "Ema, Milano passa al secondo turno di votazioni con Amsterdam e Copenhagen" (in Italian). Retrieved 20 October 2017. ^ "Brexit: People will die because of plans to set up UK-only drug regulator, cancer specialist warns". Independent. 10 February 2017. Retrieved 11 February 2017. ^ "Our news".. ^ Louise Brinth: Responsum to Assessment Report on HPV-vaccines released by EMA November 26th 2015., online (PDF; 1, 3 MB) ^ Gu, A; Patel, D; Nayak, R (2016). "Chapter 10: Drug shortages". In Fulda, TR; Lyles, A; Wertheimer (eds. ). Pharmaceutical Public Policy. CRC Press. pp. 151–160. ISBN 9781498748513. ^ Boslaugh, SE (2015). "European Medicines Agency". The SAGE Encyclopedia of Pharmacology and Society. SAGE Publications. ISBN 9781506346182. ^ Sherwood, Ted (16 April 2008). "Generic Drugs: Overview of ANDA Review Process" (PDF). Food and Drug Administration. Archived from the original (PDF) on 19 January 2017. Retrieved 30 January 2010. Further reading [ edit] McCormick, John (2004). The European Union: Politics and Policies. Boulder, Colo: Westview Press. ISBN 0-8133-4202-3. External links [ edit] Official website EMA Annual Report 2018 Heads of Medicines Agencies The Rules Governing Medicinal Products in the European Union (EudraLex) Health-EU Portal official public health portal of the European Union.
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